beauty
cleaning
food
industrial

alpha-Vitamin E

CAS 21-59-0 · 40/100 · High conf.

Also registered as 10 other CAS numbers

2074-53-5 · 364-49-8 · 18920-62-2 · 121854-78-2 · 2484908-93-0 · 59-02-9 · 119-13-1 · 1406-18-4 · 1406-66-2 · 7616-22-0

Concern score

40/100Moderate concern based on regulatory listings.

High confidence

alpha-Vitamin E in plain language

What it is: On cosmetic ingredient lists it appears as “Tocopherol”.
Also known as Tocopherol · .alpha.-tocopherol · Alpha-tocopherol · D-alpha tocopherol · Rrr-alpha-tocopherol concentrate · .alpha.-tocopherol, d-
Show all 36 names
5,7,8-TRIMETHYLTOCOL · Mixed TOCOPHEROLS concentrate · RRR-alpha-Tocopherol · mixed TOCOPHEROL CONCENTRATE · Vitamin E · (+)-alpha-tocopherol- · R,r,r-.alpha.-tocopherol · Tocopherol, d-alpha- · Vitamin e d-alpha · (+)-(2R,4′R,8′R)-α-Tocopherol · (+)-α-Tocopherol · (2R,4'R,8'R)-α-Tocopherol · Alpha-tocopherol, d- · Bio-e-vit · Davina · E Vitamin · E-307A · E-caps · Fort-e-vite · Fort-e-vite 1000 · Fort-e-vite plus · Harris · Ins NO.307A · INS-307A · J24.260H · Jarrow for · Vitamin E (USP) · Vitamin E Compound · alpha tocopherol · d-alpha-tocopherol
What it does: Used in cosmetics as an antioxidant, an occlusive and a skin-conditioning agent. Tocopherol consists of alpha-tocopherol, beta-tocopherol, delta-tocopherol and/or gamma-tocopherol.
Antioxidant
Occlusive
Skin conditioning
Fragrance
Preservative
Conditioner
Is it a concern?: Moderate concern: no hazard classifications on record. It is listed for cosmetic use in the EU.

Why it's flagged

EPA CPDat observed this chemical in 33 composition records across product categories including Industrial products, Laboratory supplies, Personal care.

The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.

Regulation

No restrictions found. alpha-Vitamin E appears in these published regulatory listings.

Recorded in these product areas

Found in consumer products
Beauty
Cleaning
Pharma
Food
Industrial

EUEFSAEFSA opinion7 entries
- Assessment of a feed additive consisting of RRR-alphatocopheryl acetate (vitamin E) for all animal species for the renewal of its authorisation (Specialty Ingredients (Europe) B.V. and Vitae Caps S.A.) (EFSA FEEDAP)Source →
- Assessment of a feed additive consisting of all-rac-alpha tocopheryl acetate (vitamin E) for all animal species for the renewal of its authorisation (EUROPE-ASIA Import Export GmbH) (EFSA FEEDAP)Source →
- Assessment of a feed additive consisting of all-rac-alpha tocopheryl acetate (vitamin E) for all animal species for the renewal of its authorisation (DSM) (EFSA FEEDAP)Source →
- Assessment of a feed additive consisting of all-rac-alphatocopheryl acetate (vitamin E) for all animal species for the renewal of its authorisation (NHU Europe GmbH) (EFSA FEEDAP)Source →
- Opinion on mixed tocopherols, tocotrienol tocopherol and tocotrienols as sources for vitamin E added as a nutritional substance in food supplements - Scientific Opinion of the Panel on Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food (EFSA AFC)Source →
- Scientific Opinion on the safety and efficacy of vitamin E as a feed additive for all animal species (EFSA FEEDAP)Source →
- Assessment of a feed additive consisting of all-rac-alpha tocopheryl acetate (vitamin E) for all animal species for the renewal of its authorisation (BASF SE) (EFSA FEEDAP)Source →
GLOBALJECFAEvaluated2 entries
- JECFA evaluation record.Source →
- JECFA evaluation record. Functional class: antioxidant.Source →
EUCosIngActiveTocopherol consists of alpha-tocopherol, beta-tocopherol, delta-tocopherol and/or gamma-tocopherol and conforms to the formulae:
- Tocopherol consists of alpha-tocopherol, beta-tocopherol, delta-tocopherol and/or gamma-tocopherol and conforms to the formulae:Source →
EUEFSAReport from international authorityOpinion of the Scientific Committee on Food on the Tolerable Upper Intake Level of Vitamin E (SCF)
- Opinion of the Scientific Committee on Food on the Tolerable Upper Intake Level of Vitamin E (SCF)Source →
GLOBALJECFA0-2 mg/kg bwJECFA evaluation lists ADI 0-2 mg/kg bw. Functional class: antioxidant.
- JECFA evaluation lists ADI 0-2 mg/kg bw. Functional class: antioxidant.Source →
USEPAcommercial use observedEPA CPDat observed this chemical in 33 composition records across product categories including Industrial products, Laboratory supplies, Personal care. EPA CPDat classifies this chemical for functional uses including Softener and conditioner, Binder, Fragrance.
- EPA CPDat observed this chemical in 33 composition records across product categories including Industrial products, Laboratory supplies, Personal care. EPA CPDat classifies this chemical for functional uses including Softener and conditioner, Binder, Fragrance.Source →
USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
- openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

Independent scientific assessments cited by the records we hold, with the year and link where the record gives one.

SCCS
EU Scientific Committee on Consumer Safety
No SCCS opinion on file.
CIR
Cosmetic Ingredient Review (US expert panel)
No CIR safety assessment on file.
EFSA
European Food Safety Authority
- Opinion of the Scientific Committee on Food on the Tolerable Upper Intake Level of Vitamin E (SCF)
  2003 · EU EFSA listing · Read the source →
- Assessment of a feed additive consisting of RRR-alphatocopheryl acetate (vitamin E) for all animal species for the renewal of its authorisation (Specialty Ingredients (Europe) B.V. and Vitae Caps S.A.) (EFSA FEEDAP)
  2021 · EU EFSA listing · Read the source →
- Assessment of a feed additive consisting of all-rac-alpha tocopheryl acetate (vitamin E) for all animal species for the renewal of its authorisation (EUROPE-ASIA Import Export GmbH) (EFSA FEEDAP)
  2021 · EU EFSA listing · Read the source →
- Assessment of a feed additive consisting of all-rac-alpha tocopheryl acetate (vitamin E) for all animal species for the renewal of its authorisation (DSM) (EFSA FEEDAP)
  2021 · EU EFSA listing · Read the source →
- Assessment of a feed additive consisting of all-rac-alphatocopheryl acetate (vitamin E) for all animal species for the renewal of its authorisation (NHU Europe GmbH) (EFSA FEEDAP)
  2021 · EU EFSA listing · Read the source →
- Opinion on mixed tocopherols, tocotrienol tocopherol and tocotrienols as sources for vitamin E added as a nutritional substance in food supplements - Scientific Opinion of the Panel on Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food (EFSA AFC)
  2008 · EU EFSA listing · Read the source →
- Scientific Opinion on the safety and efficacy of vitamin E as a feed additive for all animal species (EFSA FEEDAP)
  2010 · EU EFSA listing · Read the source →
- Assessment of a feed additive consisting of all-rac-alpha tocopheryl acetate (vitamin E) for all animal species for the renewal of its authorisation (BASF SE) (EFSA FEEDAP)
  2021 · EU EFSA listing · Read the source →
JECFA
Joint FAO/WHO Expert Committee on Food Additives
- JECFA evaluation lists ADI 0-2 mg/kg bw. Functional class: antioxidant.
  Year not recorded · GLOBAL JECFA listing · Read the source →
- JECFA evaluation record.
  Year not recorded · GLOBAL JECFA listing · Read the source →
- JECFA evaluation record. Functional class: antioxidant.
  Year not recorded · GLOBAL JECFA listing · Read the source →

Evidence & sources

No graded research studies for alpha-Vitamin E yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

8 data sources

Where this comes from

CosIng
regulatory · updated 2026-09-23
Open →
EFSA OpenFoodTox
regulatory · updated 2026-10-04
Open →
EPA Chemical and Products Database
exposure · updated may 30, 2017
Open →
EPA DSSTox Identifiers
chemistry · updated 2025-12-29
Open →
FDA GSRS UNII
registry · updated 2026-02-26
Open →
WHO JECFA Database
regulatory · updated 2026-10-04
Open →
openFDA Substance
registry · updated 2026-05-24
Open →
PubChem Live Enrichment
chemistry · updated 2026-05-17
Open →

Reference links (3)

Openfda substance

fao.org

Read →

Openfda substance

codexalimentarius.net

Read →

Openfda substance

nikkajiweb.jst.go.jp

Read →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Food use

Food-use source coverage is present in the current record.

Good fit

The ingredient appears in food-oriented source coverage or allowed-use references, which makes food use easier to support than a context with no domain signal at all.

Fragrance avoidance

Not a strong fit for fragrance avoidance because it carries Fragrance.

Avoid

The ingredient itself is a fragrance-linked signal, so it is better treated as an avoid case when fragrance exposure is the main concern.

Where it has been recorded

How often EPA CPDat has listed alpha-Vitamin E in a product composition. These are source records, not Greenveil catalog products.

Source records

Named organisations

Industrial productsLaboratory suppliesPersonal careConstruction and building materialsFood and drugCleaning products and household care

Typical roles

AntioxidantOcclusiveSkin conditioningFragrancePreservativeConditioner

See products using alpha-Vitamin E →

Catalog

Found in these products

Their ingredient lists include alpha-Vitamin E; each product's own rating depends on its whole formula, so it is shown on the product page, not here.

See all 1000+ →Find products without it →

Co-occurrence

Often appears with

Ingredients that frequently appear alongside alpha-Vitamin E in the catalog.