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  • cleaning
  • food

DL-Valine

CAS 516-06-3 · 40/100 · High conf.

Also registered as 3 other CAS numbers

25609-85-2 · 186023-77-8 · 1105707-15-0

DL-Valine chemical structure

Concern score

40/100Moderate concern based on regulatory listings.
High confidence

DL-Valine in plain language

What it is

Also known as D,l-valine · 2-AMINO-3-METHYLBUTANOIC acid · Valine, dl- · Valine · (+/-)-2-AMINOISOVALERIC acid · (+/-)-2-Amino-3-methylbutyric acid

Show all 22 names

(+/-)-valine · (±)-2-AMINO-3-METHYLBUTYRIC acid · (±)-2-AMINOISOVALERIC acid · (±)-valine · 2-AMINO-3-METHYLBUTYRIC acid · 2-AMINOISOVALERIC acid · 2-Amino-3-methylbutanoic acid (VAN) · 2Amino3methylbutanoic acid, DL · 2Amino3methylbutyric acid, DL · 2Aminoisovaleric acid, DL · DL-Val · DL-valin · DL-α-Aminoisovaleric acid · H-DL-Val-OH · RS-Valine · DL alphaAminoisovaleric acid

What it does

Used in food as a flavouring agent.

  • Flavouring agent
  • Fragrance
  • Flavouring
  • Conditioner
  • Antistatic
  • Deodorant
Is it a concern?
Moderate concern: no hazard classifications on record.

Why it's flagged

EPA CPDat observed this chemical in 125 composition records across product categories including Personal care.

The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.

Regulation

No restrictions found. DL-Valine appears in these published regulatory listings.

Recorded in these product areas

  • Found in consumer products
  • Beauty
  • Cleaning
  • EUEFSAEFSA opinionFlavouring Group Evaluation 79, (FGE.79). Consideration of amino acids and related substances evaluated by JECFA (63rd meeting) structurally related to amino acids from chemical group 34 evaluated by EFSA in FGE.26Rev1 (2008). Scientific Opinion of the Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food (EFSA AFC)
    • Flavouring Group Evaluation 79, (FGE.79). Consideration of amino acids and related substances evaluated by JECFA (63rd meeting) structurally related to amino acids from chemical group 34 evaluated by EFSA in FGE.26Rev1 (2008). Scientific Opinion of the Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food (EFSA AFC)Source →
  • GLOBALJECFANo safety concern at current levels of intake when used as a flavouring agentJECFA evaluation lists ADI No safety concern at current levels of intake when used as a flavouring agent. Functional class: flavouring agent.
    • JECFA evaluation lists ADI No safety concern at current levels of intake when used as a flavouring agent. Functional class: flavouring agent.Source →
  • GLOBALJECFAEvaluatedJECFA evaluation record.
  • USEPAcommercial use observedEPA CPDat observed this chemical in 125 composition records across product categories including Personal care. EPA CPDat classifies this chemical for functional uses including Anti-static agent, Deodorizer, Softener and conditioner.
    • EPA CPDat observed this chemical in 125 composition records across product categories including Personal care. EPA CPDat classifies this chemical for functional uses including Anti-static agent, Deodorizer, Softener and conditioner.Source →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
    • openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

Independent scientific assessments cited by the records we hold, with the year and link where the record gives one.

  • JECFA

    Joint FAO/WHO Expert Committee on Food Additives

    • JECFA evaluation lists ADI No safety concern at current levels of intake when used as a flavouring agent. Functional class: flavouring agent.

      Year not recorded · GLOBAL JECFA listing · Read the source →

    • JECFA evaluation record.

      Year not recorded · GLOBAL JECFA listing · Read the source →

  • EFSA

    European Food Safety Authority

    • Flavouring Group Evaluation 79, (FGE.79). Consideration of amino acids and related substances evaluated by JECFA (63rd meeting) structurally related to amino acids from chemical group 34 evaluated by EFSA in FGE.26Rev1 (2008). Scientific Opinion of the Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food (EFSA AFC)

      2008 · EU EFSA listing · Read the source →

Evidence & sources

No graded research studies for DL-Valine yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

7 data sources

Where this comes from

  • EFSA OpenFoodTox

    regulatory · updated 2026-10-04

    Open →
  • EPA Chemical and Products Database

    exposure · updated September 2018

    Open →
  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →
  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →
  • WHO JECFA Database

    regulatory · updated 2026-10-04

    Open →
  • openFDA Substance

    registry · updated 2026-05-24

    Open →
  • PubChem Live Enrichment

    chemistry · updated 2026-05-17

    Open →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Food use

Food-use source coverage is present in the current record.

Good fit

The ingredient appears in food-oriented source coverage or allowed-use references, which makes food use easier to support than a context with no domain signal at all.

Fragrance avoidance

Not a strong fit for fragrance avoidance because it carries Fragrance.

Avoid

The ingredient itself is a fragrance-linked signal, so it is better treated as an avoid case when fragrance exposure is the main concern.

Where it has been recorded

How often EPA CPDat has listed DL-Valine in a product composition. These are source records, not Greenveil catalog products.

Source records

125

Named organisations

6

Personal care

Typical roles

Flavouring agentFragranceFlavouringConditionerAntistaticDeodorant
See products using DL-Valine →

Catalog

Found in these products

Their ingredient lists include DL-Valine; each product's own rating depends on its whole formula, so it is shown on the product page, not here.

Co-occurrence

Often appears with

Ingredients that frequently appear alongside DL-Valine in the catalog.