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  • beauty
  • cleaning
  • food

Isoleucine, dl-

CAS 443-79-8 · 40/100 · High conf.

Also registered as 9 other CAS numbers

19883-67-1 · 198412-80-5 · 205879-85-2 · 224311-99-3 · 228416-77-1 · 676371-21-4 · 1160211-67-5 · 1649424-38-3 · 1798874-13-1

Concern score

40/100Moderate concern based on regulatory listings.
High confidence

Isoleucine, dl- in plain language

What it is

Also known as Dl-isoleucine · Isoleucine dl-form · 2-AMINO-3-METHYLPENTANOIC acid · Isoleucine · (±)-ERYTHRO-2-AMINO-3-METHYLPENTANOIC acid · L-Isoleucine

Show all 10 names

(+/-)-ERYTHRO-2-AMINO-3-METHYLPENTANOIC acid · (+/-)-Isoleucine · DL-Ile · d,l-Isoleucine

What it does

Used in food as a flavouring agent.

  • Flavouring agent
  • Flavouring
Is it a concern?
Moderate concern: no hazard classifications on record.

Why it's flagged

EPA CPDat observed this chemical in 4 composition records across product categories including Personal care.

The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.

Regulation

No restrictions found. Isoleucine, dl- appears in these published regulatory listings.

Recorded in these product areas

  • Found in consumer products
  • Beauty
  • Cleaning
  • GLOBALJECFAEvaluatedJECFA evaluation record.
  • GLOBALJECFANo safety concern at current levels of intake when used as a flavouring agentJECFA evaluation lists ADI No safety concern at current levels of intake when used as a flavouring agent. Functional class: flavouring agent.
    • JECFA evaluation lists ADI No safety concern at current levels of intake when used as a flavouring agent. Functional class: flavouring agent.Source →
  • USEPAcommercial use observedEPA CPDat observed this chemical in 4 composition records across product categories including Personal care. EPA CPDat classifies this chemical for functional uses including Flavouring and nutrient.
    • EPA CPDat observed this chemical in 4 composition records across product categories including Personal care. EPA CPDat classifies this chemical for functional uses including Flavouring and nutrient.Source →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
    • openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

Independent scientific assessments cited by the records we hold, with the year and link where the record gives one.

  • JECFA

    Joint FAO/WHO Expert Committee on Food Additives

    • JECFA evaluation record.

      Year not recorded · GLOBAL JECFA listing · Read the source →

    • JECFA evaluation lists ADI No safety concern at current levels of intake when used as a flavouring agent. Functional class: flavouring agent.

      Year not recorded · GLOBAL JECFA listing · Read the source →

  • EFSA

    European Food Safety Authority

    No EFSA opinion on file.

Evidence & sources

No graded research studies for Isoleucine, dl- yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

5 data sources

Where this comes from

  • EPA Chemical and Products Database

    exposure · updated June 2017

    Open →
  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →
  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →
  • WHO JECFA Database

    regulatory · updated 2026-10-04

    Open →
  • openFDA Substance

    registry · updated 2026-05-24

    Open →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Food use

Food-use source coverage is present in the current record.

Good fit

The ingredient appears in food-oriented source coverage or allowed-use references, which makes food use easier to support than a context with no domain signal at all.

Fragrance avoidance

No fragrance-linked caution surfaced in the current profile.

Good fit

This ingredient does not currently read as a fragrance-linked driver in the published evidence and hazard profile.

Where it has been recorded

How often EPA CPDat has listed Isoleucine, dl- in a product composition. These are source records, not Greenveil catalog products.

Source records

4

Named organisations

4

Personal care

Typical roles

Flavouring agentFlavouring
See products using Isoleucine, dl- →

Catalog

Found in these products

Their ingredient lists include Isoleucine, dl-; each product's own rating depends on its whole formula, so it is shown on the product page, not here.

Co-occurrence

Often appears with

Ingredients that frequently appear alongside Isoleucine, dl- in the catalog.