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  • industrial
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Threonine

CAS 6028-28-0 · 0/100 · High conf.

Also registered as 11 other CAS numbers

7013-32-3 · 13095-55-1 · 25275-17-6 · 36676-50-3 · 154605-64-8 · 154605-68-2 · 1043597-96-1 · 1370710-06-7 · 1644578-86-8 · 72-19-5 · 80-68-2

Threonine chemical structure

Concern score

0/100Low concern — well-established and permitted without restriction (CIR safe as used; EU CosIng).
High confidence

Threonine in plain language

What it is

Also known as L-threonine · (2S,3R)-2-amino-3-hydroxybutanoic acid · Thr · (2S)-threonine · (2S,3R)-(-)-Threonine · (2S,3R)-2-AMINO-3-HYDROXYBUTYRIC acid

Show all 18 names

(S)-Threonine · 2-Amino-3-hydroxybutanoic acid · 2-Amino-3-hydroxybutyric acid · L-(-)-Threonine · L-2-Amino-3-hydroxybutyric acid · L-Threonin · L-alpha-Amino-beta-hydroxybutyric acid · L-thr · Threonine, l- · Threonin · Threoninum · Treonina

What it does

Used in cosmetics as a hair conditioner, a hair waving or straightening agent and an antistatic agent.

  • Hair conditioning
  • Hair waving or straightening
  • Antistatic
  • Flavouring
Is it a concern?
Low concern: no hazard classifications on record. It is listed for cosmetic use in the EU.

Why it's flagged

EPA CPDat observed this chemical in 1 composition records across product categories including Laboratory supplies.

The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.

Regulation

No restrictions found. Threonine appears in these published regulatory listings.

  • In marketed US drugs
  • Inactive ingredient in US drugs

Recorded in these product areas

  • Found in consumer products
  • Industrial
  • USFDAinactive ingredient database3 entries
    • Route: INTRAVENOUS; Dosage form: INJECTION; Potency: 0.45 %w/vSource →
    • Route: INTRAVENOUS; Dosage form: INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION; Potency: 160 mgSource →
    • Route: INTRAVENOUS; Dosage form: INJECTION, SOLUTION; Potency: 0.12 %w/vSource →
  • EUCosIngActiveListed in CosIng inventory for cosmetic use.
    • Listed in CosIng inventory for cosmetic use.Source →
  • USEPAcommercial use observedEPA CPDat observed this chemical in 1 composition records across product categories including Laboratory supplies. EPA CPDat classifies this chemical for functional uses including Flavouring and nutrient.
    • EPA CPDat observed this chemical in 1 composition records across product categories including Laboratory supplies. EPA CPDat classifies this chemical for functional uses including Flavouring and nutrient.Source →
  • USFDAmarketed drug occurrenceFDA NDC lists this ingredient in 59 active drug products and 59 total products.
    • FDA NDC lists this ingredient in 59 active drug products and 59 total products.Source →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
    • openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

No expert opinion on file for Threonine. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

Evidence & sources

No graded research studies for Threonine yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

8 data sources

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →

  • EPA Chemical and Products Database

    exposure · updated February 8, 2019

    Open →

  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →

  • FDA Inactive Ingredient Database

    regulatory · updated 2026-01-09

    Open →

  • FDA National Drug Code Directory

    regulatory · updated 2027-12-31

    Open →

  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →

  • openFDA Substance

    registry · updated 2026-05-24

    Open →

  • PubChem Live Enrichment

    chemistry · updated 2026-05-17

    Open →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Fragrance avoidance

No fragrance-linked caution surfaced in the current profile.

Good fit

This ingredient does not currently read as a fragrance-linked driver in the published evidence and hazard profile.

Where it has been recorded

How often FDA National Drug Code directory has listed Threonine in a product composition. These are source records, not Greenveil catalog products.

Source records

59

Typical roles

Hair conditioningHair waving or straighteningAntistaticFlavouring
See products using Threonine →

Catalog

Found in these products

Cosmetic and personal-care products that list Threonine are shown first. Their ingredient lists include Threonine; each product's own rating depends on its whole formula, so it is shown on the product page, not here.

See all 201 →Find products without it →

Co-occurrence

Often appears with

Ingredients that frequently appear alongside Threonine in the catalog.