beauty
cleaning
food
industrial

Squalane

CAS 2101721-37-1 · 0/100 · High conf.

Also registered as 1 other CAS number

111-01-3

Concern score

0/100Low concern — well-established and permitted without restriction (CIR safe as used; EU CosIng).

High confidence

Squalane in plain language

What it is: Also known as 2,6,10,15,19,23-Hexamethyltetracosane · 2,6,10,15,19,23-Hexamethyltetra-cosane · 2,6,10,15,19,23-Hexamethyltetracosan · 2,6,10,15,19,23-hexametiltetracosano · Cetiol SQ · Collagen moisturizing cream
Show all 21 names
Cosbiol · Dodecahydrosqualene · GZE Sweat Stick · Hexamethyltetracosane · Hexamethyl tetracosane · Pripure 3759 · Purple hair mask · Rearoyafootcream · Robane · Spinacane · Tetracosane, 2,6,10,15,19,23-hexamethyl- · Vitabiosol · footcream · perhydrosqualene · squalane (hexamethyltetracosane)
What it does: Used in cosmetics as an emollient, a skin-conditioning agent and a hair conditioner.
Emollient
Skin conditioning
Hair conditioning
Refatting
Humectant
Conditioner
Is it a concern?: Low concern: no hazard classifications on record. It is listed for cosmetic use in the EU.

Why it's flagged

EPA CPDat observed this chemical in 3237 composition records across product categories including Food and drug, Personal care, Construction.

The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.

Regulation

No restrictions found. Squalane appears in these published regulatory listings.

In marketed US drugs
Inactive ingredient in US drugs

Recorded in these product areas

Found in consumer products
Beauty
Cleaning
Pharma
Food
Industrial

USFDAinactive ingredient database5 entries — 2 administration routes
- Route: ORAL; Dosage form: POWDER; Potency: 0.02 mgSource →
- Route: TOPICAL; Dosage form: AEROSOL, FOAM; Potency: 2.23 %w/wSource →
- Route: TOPICAL; Dosage form: CREAM; Potency: 6 %w/wSource →
- Route: TOPICAL; Dosage form: CREAM, AUGMENTED; Maximum daily exposure: 120 mgSource →
- Route: TOPICAL; Dosage form: SOLUTION; Potency: 1 %w/wSource →
EUCosIngActiveListed in CosIng inventory for cosmetic use.
- Listed in CosIng inventory for cosmetic use.Source →
USEPAcommercial use observedEPA CPDat observed this chemical in 3237 composition records across product categories including Food and drug, Personal care, Construction. EPA CPDat classifies this chemical for functional uses including Softener and conditioner, refatting, Biocide.
- EPA CPDat observed this chemical in 3237 composition records across product categories including Food and drug, Personal care, Construction. EPA CPDat classifies this chemical for functional uses including Softener and conditioner, refatting, Biocide.Source →
USFDAmarketed drug occurrenceFDA NDC lists this ingredient in 3 active drug products and 4 total products.
- FDA NDC lists this ingredient in 3 active drug products and 4 total products.Source →
USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
- openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

No expert opinion on file for Squalane. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

SCCS
EU Scientific Committee on Consumer Safety
No SCCS opinion on file.
CIR
Cosmetic Ingredient Review (US expert panel)
No CIR safety assessment on file.

Evidence & sources

No graded research studies for Squalane yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

8 data sources

Where this comes from

CosIng
regulatory · updated 2026-09-23
Open →
EPA Chemical and Products Database
exposure · updated September 2019
Open →
EPA DSSTox Identifiers
chemistry · updated 2025-12-29
Open →
FDA Inactive Ingredient Database
regulatory · updated 2026-01-09
Open →
FDA National Drug Code Directory
regulatory · updated 2026-12-31
Open →
FDA GSRS UNII
registry · updated 2026-02-26
Open →
openFDA Substance
registry · updated 2026-05-24
Open →
PubChem Live Enrichment
chemistry · updated 2026-05-17
Open →

Allergen profile

Canonical allergen markers detected on this ingredient. Each row is derived from the ingredient’s name or synonyms matching a known allergen class — useful when scanning a label for a specific allergy context.

DairyContains · Oral (ingested)
Source: chemindex_name_match

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Food use

Food-use source coverage is present in the current record.

Good fit

The ingredient appears in food-oriented source coverage or allowed-use references, which makes food use easier to support than a context with no domain signal at all.

Fragrance avoidance

No fragrance-linked caution surfaced in the current profile.

Good fit

This ingredient does not currently read as a fragrance-linked driver in the published evidence and hazard profile.

Where it has been recorded

How often EPA CPDat has listed Squalane in a product composition. These are source records, not Greenveil catalog products.

Source records

3,237

Named organisations

Food and drugPersonal careConstructionBatteries

Typical roles

EmollientSkin conditioningHair conditioningRefattingHumectantConditioner

See products using Squalane →

Catalog

Found in these products

Their ingredient lists include Squalane; each product's own rating depends on its whole formula, so it is shown on the product page, not here.

See all 375 →Find products without it →

Co-occurrence

Often appears with

Ingredients that frequently appear alongside Squalane in the catalog.