beauty
cleaning
food
industrial

Vitamin a palmitate

CAS 11103-57-4 · 70/100 · High conf.

Also registered as 8 other CAS numbers

110067-62-4 · 7488-89-3 · 37340-08-2 · 108066-99-5 · 674786-07-3 · 68-26-8 · 79-81-2 · 127-47-9

Concern score

70/100High concern based on regulatory listings.

High confidence

Vitamin a palmitate in plain language

What it is: On cosmetic ingredient lists it appears as “Retinol”.
Also known as Retinol · Retinyl acetate · Retinyl palmitate · Retinol palmitate · All-(e)-retinol palmitate · Vitamin a palmitate (solubilized)
Show all 25 names
Vitamin A · O~15~-Hexadecanoylretinol · Hexadecanoate retinol · Retinol, palmitate, all-trans · Retinol; Retinyl Acetate; Retinyl Palmitate · All-trans-retinyl palmitate · Aquapalm · Aquasol A · Arovit · Optovit-A · Retinol-15-3H · Retinol; vitamin A · Retinyl hexadecanoate · Vitamin A Solubilized · all-trans-Retinol palmitate · all-trans-Vitamin A palmitate · palmitate-1-14c · vitaminum a · Vitamin a (as palmitate & beta carotene)
What it does: Used in cosmetics as a skin-conditioning agent. Retinyl Acetate is the ester of Retinol and acetic acid.
Skin conditioning
Antioxidant
Colourant
Flavouring
Conditioner
Is it a concern?: High concern: no hazard classifications on record. It is restricted in EU cosmetics.

Why it's flagged

(2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraen-1-ol; [(2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraenyl] acetate; [(2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraenyl] hexadecanoate is restricted in cosmetic products under Annex III of the EU Cosmetics Regulation (EC) 1223/2009.

RestrictedEU EC — restricted

The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.

Regulation

Restrictions first, then routine listings from published regulatory sources.

In marketed US drugs
EU Annex III — restricted
EU restricted in cosmetics

Recorded in these product areas

Found in consumer products
Beauty
Cleaning
Pharma
Food
Industrial

EUEC
Annex III of EU Cosmetics Regulation (EC) 1223/2009: substances which cosmetic products must not contain except subject to the restrictions laid down. Product types: (a) Body lotion (b) other leave-on and rinse-off products Maximum concentration: (a) 0,05 % Retinol Equivalent (RE) (b) 0,3 % RE Other conditions: From 1 November 2025 cosmetic products containing that substance and not complying with the conditions shall not be placed on the Union market. From 1 May 2027 cosmetic products containing that substance and not complying with the conditions shall not be made available on the Union market. Conditions of use and warnings: For any cosmetic product containing Retinol, Retinyl Acetate or Retinyl Palmitate the following, labelling is obligatory: ‘Contains Vitamin A. Consider your daily intake before use’.
restricted
View source →

EUCosIngActive4 entries
- Cosmetics Regulation annex III / ref 376.Source →
- Retinol is the organic compound that conforms to the formula: Restriction: III/376Source →
- Retinyl Acetate is the ester of Retinol and acetic acid. Restriction: III/376Source →
- Retinyl Palmitate is the ester of Retinol and palmitic acid. Restriction: III/376Source →
EUEFSAEFSA opinion3 entries
- Scientific Opinion on the safety and efficacy of vitamin A (retinyl acetate, retinyl palmitate and retinyl propionate) as a feed additive for all animal species and categories (EFSA FEEDAP)Source →
- Scientific Opinion on Dietary Reference Values for vitamin A (EFSA NDA)Source →
- Consequences for the consumer of the use of vitamin A in animal nutrition (EFSA FEEDAP)Source →
EUEFSAReport from international authorityOpinion of the Scientific Committee on Food on the Tolerable Upper Intake Level of Preformed Vitamin A (retinol and retinyl esters) (SCF)
- Opinion of the Scientific Committee on Food on the Tolerable Upper Intake Level of Preformed Vitamin A (retinol and retinyl esters) (SCF)Source →
USEPAcommercial use observedEPA CPDat observed this chemical in 3373 composition records across product categories including Personal care, Food and drug, Construction. EPA CPDat classifies this chemical for functional uses including Softener and conditioner, Pharmaceutical, Antioxidant.
- EPA CPDat observed this chemical in 3373 composition records across product categories including Personal care, Food and drug, Construction. EPA CPDat classifies this chemical for functional uses including Softener and conditioner, Pharmaceutical, Antioxidant.Source →
USFDAmarketed drug occurrenceFDA NDC lists this ingredient in 8 active drug products and 9 total products.
- FDA NDC lists this ingredient in 8 active drug products and 9 total products.Source →
USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
- openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

Independent scientific assessments cited by the records we hold, with the year and link where the record gives one.

SCCS
EU Scientific Committee on Consumer Safety
No SCCS opinion on file.
CIR
Cosmetic Ingredient Review (US expert panel)
No CIR safety assessment on file.
EFSA
European Food Safety Authority
- Opinion of the Scientific Committee on Food on the Tolerable Upper Intake Level of Preformed Vitamin A (retinol and retinyl esters) (SCF)
  2002 · EU EFSA listing · Read the source →
- Scientific Opinion on the safety and efficacy of vitamin A (retinyl acetate, retinyl palmitate and retinyl propionate) as a feed additive for all animal species and categories (EFSA FEEDAP)
  2013 · EU EFSA listing · Read the source →
- Scientific Opinion on Dietary Reference Values for vitamin A (EFSA NDA)
  2015 · EU EFSA listing · Read the source →
- Consequences for the consumer of the use of vitamin A in animal nutrition (EFSA FEEDAP)
  2009 · EU EFSA listing · Read the source →

Evidence & sources

No graded research studies for Vitamin a palmitate yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

9 data sources

Where this comes from

CosIng
regulatory · updated 2026-09-23
Open →
EU CosIng Cosmetics Regulation Annexes
regulatory · updated 2024-04-04
Open →
EFSA OpenFoodTox
regulatory · updated 2026-10-04
Open →
EPA Chemical and Products Database
exposure · updated september 28, 2015
Open →
EPA DSSTox Identifiers
chemistry · updated 2025-12-29
Open →
FDA National Drug Code Directory
regulatory · updated 2027-12-31
Open →
FDA GSRS UNII
registry · updated 2026-02-26
Open →
openFDA Substance
registry · updated 2026-05-24
Open →
PubChem Live Enrichment
chemistry · updated 2026-05-17
Open →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Food use

Food-use source coverage is present in the current record.

Good fit

The ingredient appears in food-oriented source coverage or allowed-use references, which makes food use easier to support than a context with no domain signal at all.

Fragrance avoidance

No fragrance-linked caution surfaced in the current profile.

Good fit

This ingredient does not currently read as a fragrance-linked driver in the published evidence and hazard profile.

Where it has been recorded

How often EPA CPDat has listed Vitamin a palmitate in a product composition. These are source records, not Greenveil catalog products.

Source records

3,373

Named organisations

Personal careFood and drugConstructionRaw materialsPet and animal care

Typical roles

Skin conditioningAntioxidantColourantFlavouringConditioner

See products using Vitamin a palmitate →

Catalog

Found in these products

Their ingredient lists include Vitamin a palmitate; each product's own rating depends on its whole formula, so it is shown on the product page, not here.

See all 1000+ →Find products without it →

Co-occurrence

Often appears with

Ingredients that frequently appear alongside Vitamin a palmitate in the catalog.