Food use
Food-use source coverage is present in the current record.
The ingredient appears in food-oriented source coverage or allowed-use references, which makes food use easier to support than a context with no domain signal at all.
- beauty
- cleaning
- food
- industrial
Trisodium citrate dihydrate
CAS 2594426-28-3
Chelating agent · Crystal growth modifiers (nucleating agents) · pH regulating agent
Concern score
Not assessed — no hazard data yet.
Why it's flagged
EPA CPDat observed this chemical in 261 composition records across product categories including Laboratory supplies, Food and drug, Cleaning products and household care.
Regulation
No restrictions found. Trisodium citrate dihydrate appears in these published regulatory listings.
- commercial_presence
- consumer_product_presence
- cpdat_category:beauty|cleaning|pharma|food|industrial
- currently_marketed_ndc
- definition_level:complete
- definition_type:primary
- inactive_ingredient_database
- ingredient_type:ingredient substance
USFDAinactive ingredient database47 entries — 16 administration routes
- Route: INTRA-ARTICULAR; Dosage form: INJECTION, SOLUTION; Maximum daily exposure: 25 mgSource →
- Route: INTRACARDIAC; Dosage form: INJECTION; Maximum daily exposure: 21 mgSource →
- Route: INTRACAVERNOUS; Dosage form: INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION; Potency: 0.03 mgSource →
- Route: INTRAMUSCULAR; Dosage form: INJECTION; Maximum daily exposure: 3480 mgSource →
- Route: INTRAMUSCULAR; Dosage form: INJECTION, SOLUTION; Maximum daily exposure: 1188 mgSource →
- Route: INTRAMUSCULAR; Dosage form: SOLUTION; Potency: 0.03 %w/vSource →
- Route: INTRAOCULAR; Dosage form: INJECTION, SOLUTION, CONCENTRATE; Potency: 5.48 mg/1mlSource →
- Route: INTRAOCULAR; Dosage form: SOLUTION; Maximum daily exposure: 27 mgSource →
- Route: INTRAVENOUS; Dosage form: INJECTION; Maximum daily exposure: 3480 mgSource →
- Route: INTRAVENOUS; Dosage form: INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION; Maximum daily exposure: 800 mgSource →
- Route: INTRAVENOUS; Dosage form: INJECTION, SOLUTION; Maximum daily exposure: 1188 mgSource →
- Route: INTRAVENOUS; Dosage form: SOLUTION; Maximum daily exposure: 41 mgSource →
- Route: INTRAVITREAL; Dosage form: INJECTION, SUSPENSION; Potency: 0.17 %w/vSource →
- Route: IRRIGATION; Dosage form: INJECTION, SOLUTION, CONCENTRATE; Potency: 0.55 %w/vSource →
- Route: NASAL; Dosage form: SPRAY; Maximum daily exposure: 9 mgSource →
- Route: NASAL; Dosage form: SPRAY, METERED; Maximum daily exposure: 1 mgSource →
- Route: OPHTHALMIC; Dosage form: SOLUTION; Potency: 0.45 %w/vSource →
- Route: OPHTHALMIC; Dosage form: SOLUTION/ DROPS; Maximum daily exposure: 1 mgSource →
- Route: OPHTHALMIC; Dosage form: SUSPENSION/ DROPS; Maximum daily exposure: 7 mgSource →
- Route: ORAL; Dosage form: CAPSULE; Maximum daily exposure: 35 mgSource →
- Route: ORAL; Dosage form: CONCENTRATE; Maximum daily exposure: 104 mgSource →
- Route: ORAL; Dosage form: ELIXIR; Maximum daily exposure: 68 mgSource →
- Route: ORAL; Dosage form: GRANULE, FOR SUSPENSION; Maximum daily exposure: 4950 mgSource →
- Route: ORAL; Dosage form: POWDER, FOR SUSPENSION; Maximum daily exposure: 5010 mgSource →
- Route: ORAL; Dosage form: SOLUTION; Maximum daily exposure: 1200 mgSource →
- Route: ORAL; Dosage form: SUSPENSION; Maximum daily exposure: 5013 mgSource →
- Route: ORAL; Dosage form: SUSPENSION, EXTENDED RELEASE; Maximum daily exposure: 9 mgSource →
- Route: ORAL; Dosage form: SYRUP; Maximum daily exposure: 705 mgSource →
- Route: ORAL; Dosage form: TABLET; Maximum daily exposure: 896 mgSource →
- Route: ORAL; Dosage form: TABLET, CHEWABLE; Maximum daily exposure: 14 mgSource →
- Route: ORAL; Dosage form: TABLET, DELAYED RELEASE; Maximum daily exposure: 640 mgSource →
- Route: ORAL; Dosage form: TABLET, EXTENDED RELEASE; Maximum daily exposure: 300 mgSource →
- Route: ORAL; Dosage form: TABLET, FILM COATED, EXTENDED RELEASE; Maximum daily exposure: 200 mgSource →
- Route: RECTAL; Dosage form: SOLUTION; Maximum daily exposure: 773 mgSource →
- Route: RESPIRATORY (INHALATION); Dosage form: POWDER; Maximum daily exposure: 17 mgSource →
- Route: RESPIRATORY (INHALATION); Dosage form: SOLUTION; Maximum daily exposure: 24 mgSource →
- Route: RESPIRATORY (INHALATION); Dosage form: SUSPENSION; Maximum daily exposure: 2 mgSource →
- Route: SUBCUTANEOUS; Dosage form: INJECTION; Maximum daily exposure: 75 mgSource →
- Route: SUBCUTANEOUS; Dosage form: INJECTION, SOLUTION; Maximum daily exposure: 28 mgSource →
- Route: SUBLINGUAL; Dosage form: FILM; Maximum daily exposure: 7 mgSource →
- + 7 more entries not shown
USEPAcommercial use observedEPA CPDat observed this chemical in 261 composition records across product categories including Laboratory supplies, Food and drug, Cleaning products and household care. EPA CPDat classifies this chemical for functional uses including Chelating agent, pH regulating agent, Preservative.
- EPA CPDat observed this chemical in 261 composition records across product categories including Laboratory supplies, Food and drug, Cleaning products and household care. EPA CPDat classifies this chemical for functional uses including Chelating agent, pH regulating agent, Preservative.Source →
USFDAmarketed drug occurrenceFDA NDC lists this ingredient in 45 active drug products and 45 total products.
- FDA NDC lists this ingredient in 45 active drug products and 45 total products.Source →
USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
- openFDA substance registry classifies this ingredient as chemical.Source →
Evidence
No graded sources yet for Trisodium citrate dihydrate. We publish evidence only once a source is linked and reviewed — this ingredient is in the catalog, but has not been assessed.
Suitability
Context-specific fit derived from published classifications and the current ingredient evidence profile.
Good fit
Fragrance avoidance
No fragrance-linked caution surfaced in the current profile.
This ingredient does not currently read as a fragrance-linked driver in the published evidence and hazard profile.
Where it appears
Prevalence of Trisodium citrate dihydrate in our catalog (epa_cpdat).
Products
261
Brands
6
Laboratory suppliesFood and drugCleaning products and household careCleaning and safetyIndustrial productsPersonal care
Typical roles
Chelating agentCrystal growth modifiers (nucleating agents)pH regulating agentPreservativeStabilizing agent
Found in these products
- Cocacola zero sugarCoke ZERO · Beverages And Beverages PreparationsHigh
- ChampoingsPantene · Non Food ProductsHigh
- coca cola zeroCoca-Cola® · Beverages And Beverages PreparationsHigh
- Coconut MilkHerbal Essences · Health BeautyHigh
- HAWAI ANANAS 1lPlant Based Foods And BeveragesCritical
- PET 1.25L FUZETEA PECHE HIBFUZE TEA · Beverages And Beverages PreparationsHigh
- gel nettoyantLa Roche-Posay · Face Cleansing GelMinor
- Sport TriumphGilletteLow
- PerlyPerly · DairiesCritical
- ToallitasDodotMinor
- Hawai TropicalHawai, The Coca-Cola Company · Plant Based Foods And BeveragesCritical
- Mirinda POMME 1.5lMirinda · Beverages And Beverages PreparationsCritical
- Thé noir glacé saveur pêche intenseFuze Tea · Beverages And Beverages PreparationsHigh
- Fanta orangeFanta · Beverages And Beverages PreparationsHigh
- Dessert gourmand chocolatChergui · DairiesHigh
- Fanta citron 33clFanta · Plant Based Foods And BeveragesHigh
- Fuzetea thé vert infuséFuze Tea · Plant Based Foods And BeveragesHigh
- BTE 50CL MONSTER MANGO LOCMonster · Beverages And Beverages PreparationsCritical
- Champú PANTENEttyw · Non Food ProductsHigh
- linguettes HUGGIES pureHuggies · AccessoriesLow
- Bioderma sensibio gel moussant 200mlHigh
- Danacol fruits panache 125 g x 8Danacol, Danacol fruits, Danone · DairiesHigh
- SpriteSprite · Beverages And Beverages PreparationsModerate
- Kola Granulada Tarrito RojoJGB · Dietary SupplementsHigh
Often appears with
Ingredients that frequently appear alongside Trisodium citrate dihydrate in the catalog.