Food use
Food-use source coverage is present in the current record.
The ingredient appears in food-oriented source coverage or allowed-use references, which makes food use easier to support than a context with no domain signal at all.
- beauty
- food
- industrial
Diacetyl
CAS 1173018-75-1 · 60/100 · High conf.
Also registered as 2 other CAS numbers
151677-70-2 · 431-03-8
Concern score
60/100High concern based on regulatory listings.
High confidence
Diacetyl in plain language
Also known as 2,3-Butanedione · Butanedione · Dimethylglyoxal · Butane-2,3-dione · 2,3-Butadione · 2,3-Diketobutane
Show all 14 names
2,3-Dioxobutane · 2,3-butandione · BUTA-2,3-DIONE · Biacetyl · Dimethyl diketone · Diketobutane · Dimethyl glyoxal · Glyoxal, dimethyl-
Used in cosmetics as a fragrance ingredient.
- Perfuming
- Flavouring agent
- Fragrance
- Flavouring
- High concern: no hazard classifications on record. It is listed for cosmetic use in the EU.
Why it's flagged
EPA CPDat observed this chemical in 4 composition records across product categories including Laboratory supplies, Raw materials.
The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.
Regulation
No restrictions found. Diacetyl appears in these published regulatory listings.
- Found in consumer products
- Industrial
EUCosIngActiveListed in CosIng inventory for cosmetic use.
- Listed in CosIng inventory for cosmetic use.Source →
EUEFSAEFSA opinionSafety and efficacy of secondary aliphatic saturated or unsaturated alcohols, ketones, ketals and esters with a second secondary or tertiary oxygenated functional group belonging to chemical group 10 when used as flavourings for all animal species (EFSA FEEDAP)
- Safety and efficacy of secondary aliphatic saturated or unsaturated alcohols, ketones, ketals and esters with a second secondary or tertiary oxygenated functional group belonging to chemical group 10 when used as flavourings for all animal species (EFSA FEEDAP)Source →
EUEFSAEFSA statementEvaluation of a scientific publication associating diacetyl with enhancement of -amyloid-induced neurotoxicity. European Food Safety Authority (EFSA CEF)
- Evaluation of a scientific publication associating diacetyl with enhancement of -amyloid-induced neurotoxicity. European Food Safety Authority (EFSA CEF)Source →
GLOBALJECFAEvaluatedJECFA evaluation record.
- JECFA evaluation record.Source →
GLOBALJECFANo safety concern at current levels of intake when used as a flavouring agentJECFA evaluation lists ADI No safety concern at current levels of intake when used as a flavouring agent. Functional class: flavouring agent.
- JECFA evaluation lists ADI No safety concern at current levels of intake when used as a flavouring agent. Functional class: flavouring agent.Source →
USEPAcommercial use observedEPA CPDat observed this chemical in 4 composition records across product categories including Laboratory supplies, Raw materials. EPA CPDat classifies this chemical for functional uses including Fragrance, Flavouring and nutrient, Protectors and Developers.
- EPA CPDat observed this chemical in 4 composition records across product categories including Laboratory supplies, Raw materials. EPA CPDat classifies this chemical for functional uses including Fragrance, Flavouring and nutrient, Protectors and Developers.Source →
USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
- openFDA substance registry classifies this ingredient as chemical.Source →
Expert safety opinions
Independent scientific assessments cited by the records we hold, with the year and link where the record gives one.
SCCS
EU Scientific Committee on Consumer Safety
No SCCS opinion on file.
CIR
Cosmetic Ingredient Review (US expert panel)
No CIR safety assessment on file.
EFSA
European Food Safety Authority
Safety and efficacy of secondary aliphatic saturated or unsaturated alcohols, ketones, ketals and esters with a second secondary or tertiary oxygenated functional group belonging to chemical group 10 when used as flavourings for all animal species (EFSA FEEDAP)
2016 · EU EFSA listing · Read the source →
Evaluation of a scientific publication associating diacetyl with enhancement of -amyloid-induced neurotoxicity. European Food Safety Authority (EFSA CEF)
2013 · EU EFSA listing · Read the source →
JECFA
Joint FAO/WHO Expert Committee on Food Additives
JECFA evaluation record.
Year not recorded · GLOBAL JECFA listing · Read the source →
JECFA evaluation lists ADI No safety concern at current levels of intake when used as a flavouring agent. Functional class: flavouring agent.
Year not recorded · GLOBAL JECFA listing · Read the source →
Evidence & sources
No graded research studies for Diacetyl yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.
Where this comes from
- Open →
CosIng
regulatory · updated 2026-09-23
- Open →
EFSA OpenFoodTox
regulatory · updated 2026-10-04
- Open →
EPA Chemical and Products Database
exposure · updated February 8, 2019
- Open →
EPA DSSTox Identifiers
chemistry · updated 2025-12-29
- Open →
FDA GSRS UNII
registry · updated 2026-02-26
- Open →
WHO JECFA Database
regulatory · updated 2026-10-04
- Open →
openFDA Substance
registry · updated 2026-05-24
- Open →
PubChem Live Enrichment
chemistry · updated 2026-05-17
Suitability
Context-specific fit derived from published classifications and the current ingredient evidence profile.
Good fit
Fragrance avoidance
Not a strong fit for fragrance avoidance because it carries Fragrance.
The ingredient itself is a fragrance-linked signal, so it is better treated as an avoid case when fragrance exposure is the main concern.
Where it has been recorded
How often EPA CPDat has listed Diacetyl in a product composition. These are source records, not Greenveil catalog products.
Source records
4
Named organisations
5
Laboratory suppliesRaw materials
Typical roles
PerfumingFlavouring agentFragranceFlavouring
Found in these products
Their ingredient lists include Diacetyl; each product's own rating depends on its whole formula, so it is shown on the product page, not here.
