- beauty
- cleaning
- food
- industrial
Hyaluronic acid
CAS 9004-61-9 · 0/100 · High conf.
Also registered as 13 other CAS numbers
9039-38-7 · 29382-75-0 · 37243-73-5 · 165324-65-2 · 953845-54-0 · 953845-55-1 · 953845-56-2 · 953845-57-3 · 1257406-45-3 · 1357910-24-7 · 1444006-49-8 · 1623804-64-7 · 1623804-65-8
Concern score
0/100Low concern — well-established and permitted without restriction (CIR safe as used; EU CosIng).
High confidence
Hyaluronic acid in plain language
Also known as Hyaluronan · Hyaluronate · Hyaluronic acid (streptococcus equi) · ACP gel · Acide hyaluronique · Bio Hyaluro 9
Show all 11 names
Chlamyhyaluronic acid · Cystitat · Durolane · Genzyme 9983 · acido hialuronico
Used in cosmetics as a humectant, a moisturiser and a skin-conditioning agent.
- Humectant
- Moisturising
- Skin conditioning
- Antistatic
- Thickener
- Flavouring
- Low concern: no hazard classifications on record. It is listed for cosmetic use in the EU.
Why it's flagged
Fetched 1 ClinicalTrials.gov references for HYALURONIC ACID.
The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.
Regulation
No restrictions found. Hyaluronic acid appears in these published regulatory listings.
- In marketed US drugs
- Found in consumer products
- Beauty
- Cleaning
- Pharma
- Food
- Industrial
EUCosIngActiveListed in CosIng inventory for cosmetic use.
- Listed in CosIng inventory for cosmetic use.Source →
USEPAcommercial use observedEPA CPDat observed this chemical in 1084 composition records across product categories including Personal care, Food and drug, Construction. EPA CPDat classifies this chemical for functional uses including Humectant, Anti-static agent, Softener and conditioner.
- EPA CPDat observed this chemical in 1084 composition records across product categories including Personal care, Food and drug, Construction. EPA CPDat classifies this chemical for functional uses including Humectant, Anti-static agent, Softener and conditioner.Source →
USFDAmarketed drug occurrenceFDA NDC lists this ingredient in 25 active drug products and 26 total products.
- FDA NDC lists this ingredient in 25 active drug products and 26 total products.Source →
USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as polymer.
- openFDA substance registry classifies this ingredient as polymer.Source →
Expert safety opinions
No expert opinion on file for Hyaluronic acid. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.
SCCS
EU Scientific Committee on Consumer Safety
No SCCS opinion on file.
CIR
Cosmetic Ingredient Review (US expert panel)
No CIR safety assessment on file.
Evidence & sources
The graded studies and structured signals behind this record.
Where this comes from
- Open →
ClinicalTrials.gov
clinical · updated 2026-03-12
- Open →
CosIng
regulatory · updated 2026-09-23
- Open →
EPA Chemical and Products Database
exposure · updated September 2018
- Open →
EPA DSSTox Identifiers
chemistry · updated 2025-12-29
- Open →
FDA National Drug Code Directory
regulatory · updated 2027-12-31
- Open →
FDA GSRS UNII
registry · updated 2026-02-26
- Open →
openFDA Substance
registry · updated 2026-05-24
- Open →
PMC Open Access
literature · updated 2026-03-12
Reference links (6)
Effect Of Plasma Rich In Growth Factors In Knee Osteoarthritis
OBJECTIVES The overall objective of the study is to assess the effectiveness of the treatment with PRGF in the osteoarthritis of the knee. Main objective: \- To show more effectiveness after 6 months of the treatment with PRGF, with an…
Suitability
Context-specific fit derived from published classifications and the current ingredient evidence profile.
Food use
Food-use source coverage is present in the current record.
The ingredient appears in food-oriented source coverage or allowed-use references, which makes food use easier to support than a context with no domain signal at all.
Fragrance avoidance
No fragrance-linked caution surfaced in the current profile.
This ingredient does not currently read as a fragrance-linked driver in the published evidence and hazard profile.
Where it has been recorded
How often EPA CPDat has listed Hyaluronic acid in a product composition. These are source records, not Greenveil catalog products.
Source records
1,084
Named organisations
6
Personal careFood and drugConstruction
Typical roles
HumectantMoisturisingSkin conditioningAntistaticThickenerFlavouring
Found in these products
Their ingredient lists include Hyaluronic acid; each product's own rating depends on its whole formula, so it is shown on the product page, not here.
- SA Smoothing CleanserCeraVe
- centella sun creamNon Food Products
- Caffeine Solution 5% + EGCGThe Ordinary · Cafffeine
- Caffeine solutionThe Ordinary · Non Food Products
- PM Facial Moisturizing LotionCeraVe
- Hydrating Facial CleanserCeraVe · Open Beauty Facts
- Dr.Althea 147 Barrier Cream 50mlDr. Althea · Beauty
- Vegan Collagen AdvancedDietary Supplements
- Osteo Bi-flex Joint Health Triple StrengthOsteo Bi-Flex · Dietary Supplements
- Hair, Skin, NailsNature's Bounty · Dietary Supplements
- Vital Proteins Beauty Collagen Lavender LemonVital Proteins · Dietary Supplements
- Hydrolyzed Multi Collagen PeptidesSascha Fitness · Dietary Supplements
- Marine CollagenNew Leaf · Peptides
- Drink ExtraCellMatrix ECMSwissalphealth · Dietary Supplements
- Some By Me
- hydra végétalYves Rocher · Non Food Products
- Strobe cream goldFace
- Multi Patents Collagen PeptidesVEV · Snacks
- Vitamin C SerumMad Hippie · Facial Serum
- OsteoMove Extra Strength Joint CareNatural Factors · Dietary Supplements
- Collagen ShotsRejuvenated Ltd · Dietary Supplements
- Leanfit Hydrolyzed CollagenLeanfit · Dietary Supplements
- Multi Collagen peptidesDr Bergs
- Liposomal liquid supplement
Often appears with
Ingredients that frequently appear alongside Hyaluronic acid in the catalog.