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Tetrasodium glutamate diacetate

CAS 1612894-51-5 · 20/100 · High conf.

Also registered as 1 other CAS number

51981-21-6

Tetrasodium glutamate diacetate chemical structure

Concern score

20/100Minor concern based on regulatory listings.
High confidence

Tetrasodium glutamate diacetate in plain language

What it is

Also known as L-Glutamic acid, N,N-diacetic acid, tetrasodium salt · Tetrasodium N,N-bis(carboxymethyl)-L-glutamate · Glutamic acid n,n-diacetic acid sodium salt · L-glutamic acid, n,n-bis(carboxymethyl)-, sodium salt (1:4) · L-glutamic acid, n,n-bis(carboxymethyl)-, tetrasodium salt · L-glutamic acid-n,n-di(acetic acid) tetrasodium salt

Show all 13 names

N,n-bis(carboxymethyl)glutamic acid tetrasodium salt · Chelest CMG-40 · Dissolvine gl · Ec 257-573-7 · N,N-Bis(carboxymethyl)-L-glutamic Acid Tetrasodium Salt · UNII-5EHL50I4MY · tetrasodium n, n-bis(carboxylatomethyl) -l-glutamate

What it does

Used in cosmetics as a chelating agent.

  • Chelating
  • Chelating agent
  • Solvent
  • Cleaning agent
Is it a concern?
Minor concern: no hazard classifications on record. It is listed for cosmetic use in the EU.

Why it's flagged

EPA CPDat observed this chemical in 342 composition records across product categories including Cleaning products and household care, Personal care, Vehicle.

The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.

Regulation

No restrictions found. Tetrasodium glutamate diacetate appears in these published regulatory listings.

Recorded in these product areas

  • Found in consumer products
  • Beauty
  • Cleaning
  • Industrial
  • EUCosIngActiveListed in CosIng inventory for cosmetic use.
    • Listed in CosIng inventory for cosmetic use.Source →
  • EUEFSAEFSA opinionSafety and efficacy of Kelforce (L-glutamic acid, N,N-diacetic acid, tetrasodium salt (GLDA-Na4)) as a feed additive for chickens for fattening (EFSA FEEDAP)
    • Safety and efficacy of Kelforce (L-glutamic acid, N,N-diacetic acid, tetrasodium salt (GLDA-Na4)) as a feed additive for chickens for fattening (EFSA FEEDAP)Source →
  • USEPAcommercial use observedEPA CPDat observed this chemical in 342 composition records across product categories including Cleaning products and household care, Personal care, Vehicle. EPA CPDat classifies this chemical for functional uses including Chelating agent, Cleaning agent, Solvent.
    • EPA CPDat observed this chemical in 342 composition records across product categories including Cleaning products and household care, Personal care, Vehicle. EPA CPDat classifies this chemical for functional uses including Chelating agent, Cleaning agent, Solvent.Source →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
    • openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

Independent scientific assessments cited by the records we hold, with the year and link where the record gives one.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

  • EFSA

    European Food Safety Authority

    • Safety and efficacy of Kelforce (L-glutamic acid, N,N-diacetic acid, tetrasodium salt (GLDA-Na4)) as a feed additive for chickens for fattening (EFSA FEEDAP)

      2018 · EU EFSA listing · Read the source →

Evidence & sources

No graded research studies for Tetrasodium glutamate diacetate yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

7 data sources

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →

  • EFSA OpenFoodTox

    regulatory · updated 2026-10-04

    Open →

  • EPA Chemical and Products Database

    exposure · updated September 2018

    Open →

  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →

  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →

  • openFDA Substance

    registry · updated 2026-05-24

    Open →

  • PubChem Live Enrichment

    chemistry · updated 2026-05-17

    Open →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Food use

Food-use source coverage is present in the current record.

Good fit

The ingredient appears in food-oriented source coverage or allowed-use references, which makes food use easier to support than a context with no domain signal at all.

Fragrance avoidance

No fragrance-linked caution surfaced in the current profile.

Good fit

This ingredient does not currently read as a fragrance-linked driver in the published evidence and hazard profile.

Where it has been recorded

How often EPA CPDat has listed Tetrasodium glutamate diacetate in a product composition. These are source records, not Greenveil catalog products.

Source records

342

Named organisations

6

Cleaning products and household carePersonal careVehicleCleaning and safetySports equipmentLandscape/yard

Typical roles

ChelatingChelating agentSolventCleaning agent
See products using Tetrasodium glutamate diacetate →

Catalog

Found in these products

Their ingredient lists include Tetrasodium glutamate diacetate; each product's own rating depends on its whole formula, so it is shown on the product page, not here.

See all 671 →Find products without it →

Co-occurrence

Often appears with

Ingredients that frequently appear alongside Tetrasodium glutamate diacetate in the catalog.