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Panthenol

CAS 16485-10-2 · 0/100 · High conf.

Also registered as 1 other CAS number

62507-76-0

Panthenol chemical structure

Concern score

0/100Low concern — well-established and permitted without restriction (CIR safe as used; EU CosIng).
High confidence

Panthenol in plain language

What it is

Also known as Dl-panthenol · Racemic panthenol · 2,4-Dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutanamide · (+/-)-pantothenyl alcohol · (±)-2,4-DIHYDROXY-N-(3-HYDROXYPROPYL)-3,3-DIMETHYLBUTYRAMIDE · (±)-pantothenyl alcohol

Show all 27 names

2,4-Dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutyramide · AAPE Hair Ampoule · Butanamide, 2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethyl- · Butyramide, α,γ-dihydroxy-N-(3-hydroxypropyl)-β,β-dimethyl- · Dl-pantothenol · Dl-pantothenyl alcohol · ELF Perm · Eyelash Growth Serum · Panthenol Mannitol · Panthenol, dl- · Pantothenol · Pantenolo · forme-DL Panthenol · Niacinamide Panthenol · Panthenolum · Purple Toner · Roota Re F Tonic · Roota Re F for men · Roota Re V Tonic · pantenol · panthenol (racemic pantothenol)

What it does

Used in consumer products as a humectant, a fragrance ingredient and a conditioner.

  • Humectant
  • Fragrance
  • Conditioner
  • Antistatic
  • Antimicrobial
Is it a concern?
Low concern: no hazard classifications on record.

Why it's flagged

EPA CPDat observed this chemical in 11353 composition records across product categories including Personal care, Food and drug, Home maintenance.

The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.

Regulation

No restrictions found. Panthenol appears in these published regulatory listings.

  • In marketed US drugs

Recorded in these product areas

  • Found in consumer products
  • Beauty
  • Cleaning
  • Pharma
  • Food
  • Industrial
  • USEPAcommercial use observedEPA CPDat observed this chemical in 11353 composition records across product categories including Personal care, Food and drug, Home maintenance. EPA CPDat classifies this chemical for functional uses including Softener and conditioner, Humectant, Pharmaceutical.
    • EPA CPDat observed this chemical in 11353 composition records across product categories including Personal care, Food and drug, Home maintenance. EPA CPDat classifies this chemical for functional uses including Softener and conditioner, Humectant, Pharmaceutical.Source →
  • USFDAmarketed drug occurrenceFDA NDC lists this ingredient in 21 active drug products and 26 total products.
    • FDA NDC lists this ingredient in 21 active drug products and 26 total products.Source →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
    • openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

No expert opinion on file for Panthenol. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

  • JECFA

    Joint FAO/WHO Expert Committee on Food Additives

    No JECFA evaluation on file.

  • EFSA

    European Food Safety Authority

    No EFSA opinion on file.

Evidence & sources

No graded research studies for Panthenol yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

6 data sources

Where this comes from

  • EPA Chemical and Products Database

    exposure · updated september 30, 2011

    Open →
  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →
  • FDA National Drug Code Directory

    regulatory · updated 2028-02-03

    Open →
  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →
  • openFDA Substance

    registry · updated 2026-05-24

    Open →
  • PubChem Live Enrichment

    chemistry · updated 2026-05-17

    Open →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Food use

Food-use source coverage is present in the current record.

Good fit

The ingredient appears in food-oriented source coverage or allowed-use references, which makes food use easier to support than a context with no domain signal at all.

Fragrance avoidance

Not a strong fit for fragrance avoidance because it carries Fragrance.

Avoid

The ingredient itself is a fragrance-linked signal, so it is better treated as an avoid case when fragrance exposure is the main concern.

Where it has been recorded

How often EPA CPDat has listed Panthenol in a product composition. These are source records, not Greenveil catalog products.

Source records

11,353

Named organisations

6

Personal careFood and drugHome maintenanceConstructionPet and animal careRaw materials

Typical roles

HumectantFragranceConditionerAntistaticAntimicrobial
See products using Panthenol →

Catalog

Found in these products

Their ingredient lists include Panthenol; each product's own rating depends on its whole formula, so it is shown on the product page, not here.

Co-occurrence

Often appears with

Ingredients that frequently appear alongside Panthenol in the catalog.