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Copper gluconate

CAS 6020-31-1 · 40/100 · High conf.

Also registered as 4 other CAS numbers

79366-36-2 · 92266-74-5 · 115841-02-6 · 527-09-3

Copper gluconate chemical structure

Concern score

40/100Moderate concern based on regulatory listings.
High confidence

Copper gluconate in plain language

What it is

Also known as Cupric gluconate · Bis(D-gluconato-kappaO1,kappaO2)copper · Copper d-gluconate (1:2) · COPPER(2+) d-gluconate, (1:2) · Copper(ii) gluconate · Copper, bis (d-gluconato-o(sup 1),O(SUP 2))-

Show all 28 names

Cuprum gluconicum · Copper(2+) di(D-gluconate) · Gluconic acid, COPPER(2+) salt · Gluconic acid, COPPER(2+) salt (2:1), d- · copper bis((2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoate) · Bis(D-gluconato)copper · Bis(D-gluconato-O1,O2)copper · Bis(D-gluconato-κO1,κO2)copper · Copper di-D-gluconate · Copper gluconate (USP) · Copper(II) D-gluconate · Copper, bis(D-gluconato-O1,O2)- · Copper, bis(D-​gluconato-​κO1,​κO2)​- · Cupric gluconate monohydrate · copper complex D-Gluconic acid · D-Gluconic acid, copper(2+) salt · Helshas Cu · Labicuper · Pleo Cup · copper;(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoate · Copper (as gluconate) · Copper (as copper gluconate)

What it does

Used in cosmetics as a skin-conditioning agent and a skin protectant.

  • Skin conditioning
  • Skin protecting
  • Humectant
  • Flavouring
  • Conditioner
Is it a concern?
Moderate concern: no hazard classifications on record. It is listed for cosmetic use in the EU.

Why it's flagged

EPA CPDat observed this chemical in 334 composition records across product categories including Personal care, Food and drug.

The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.

Regulation

No restrictions found. Copper gluconate appears in these published regulatory listings.

Recorded in these product areas

  • Found in consumer products
  • Beauty
  • Cleaning
  • Pharma
  • Food
  • EUCosIngActiveListed in CosIng inventory for cosmetic use.
    • Listed in CosIng inventory for cosmetic use.Source →
  • EUEFSAConclusion on Pesticides Peer ReviewConclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture (EFSA)
    • Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture (EFSA)Source →
  • USEPAcommercial use observedEPA CPDat observed this chemical in 334 composition records across product categories including Personal care, Food and drug. EPA CPDat classifies this chemical for functional uses including Humectant, Softener and conditioner, No specific technical function.
    • EPA CPDat observed this chemical in 334 composition records across product categories including Personal care, Food and drug. EPA CPDat classifies this chemical for functional uses including Humectant, Softener and conditioner, No specific technical function.Source →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
    • openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

Independent scientific assessments cited by the records we hold, with the year and link where the record gives one.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

  • EFSA

    European Food Safety Authority

    • Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture (EFSA)

      2013 · EU EFSA listing · Read the source →

Evidence & sources

No graded research studies for Copper gluconate yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

7 data sources

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →
  • EFSA OpenFoodTox

    regulatory · updated 2026-10-04

    Open →
  • EPA Chemical and Products Database

    exposure · updated September 2018

    Open →
  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →
  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →
  • openFDA Substance

    registry · updated 2026-05-24

    Open →
  • PubChem Live Enrichment

    chemistry · updated 2026-05-17

    Open →
Reference links (1)
Openfda substance

drugoffice.gov.hk

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Food use

Food-use source coverage is present in the current record.

Good fit

The ingredient appears in food-oriented source coverage or allowed-use references, which makes food use easier to support than a context with no domain signal at all.

Fragrance avoidance

No fragrance-linked caution surfaced in the current profile.

Good fit

This ingredient does not currently read as a fragrance-linked driver in the published evidence and hazard profile.

Where it has been recorded

How often EPA CPDat has listed Copper gluconate in a product composition. These are source records, not Greenveil catalog products.

Source records

334

Named organisations

6

Personal careFood and drug

Typical roles

Skin conditioningSkin protectingHumectantFlavouringConditioner
See products using Copper gluconate →

Catalog

Found in these products

Their ingredient lists include Copper gluconate; each product's own rating depends on its whole formula, so it is shown on the product page, not here.

Co-occurrence

Often appears with

Ingredients that frequently appear alongside Copper gluconate in the catalog.