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.alpha.-tocopherol acetate, dl-

CAS 52225-20-4 · 40/100 · High conf.

Also registered as 5 other CAS numbers

7695-91-2 · 54-22-8 · 133-80-2 · 1407-18-7 · 18920-61-1

.alpha.-tocopherol acetate, dl- chemical structure

Concern score

40/100Moderate concern based on regulatory listings.
High confidence

.alpha.-tocopherol acetate, dl- in plain language

What it is

Also known as Dl-alpha tocopheryl acetate · All-rac-alpha-tocopheryl acetate · Dl-.alpha.-tocopherol acetate · dl-alpha-Tocopheryl acetate · .alpha.-tocopherol acetate, all-racemic · .alpha.-tocopherol acetate, dl-, dl-, dl-

Show all 14 names

.alpha.-tocopheryl acetate, dl- · All-rac-alfa-tocopheryl acetate · Dl-.alpha.-tocopheryl acetate · Tocopheryl acetate, dl-.alpha. · (+/-)-α-Tocopherol acetate · Alpha-tocopherol acetate, dl- · J262.912G · Vitamin E acetate (dl-form)

What it does

We don't have a plain-language description for .alpha.-tocopherol acetate, dl- yet.

Is it a concern?
Moderate concern: no hazard classifications on record.

Why it's flagged

EPA CPDat observed this chemical in 1 composition records across product categories including Personal care.

The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.

Regulation

No restrictions found. .alpha.-tocopherol acetate, dl- appears in these published regulatory listings.

  • In marketed US drugs
  • Inactive ingredient in US drugs

Recorded in these product areas

  • Found in consumer products
  • Beauty
  • EUEFSAEFSA opinion3 entries
    • Assessment of a feed additive consisting of all-rac-alphatocopheryl acetate (vitamin E) for all animal species for the renewal of its authorisation (Jilin Beisha Pharmaceutical Co., Ltd) (EFSA FEEDAP)Source →
    • Scientific Opinion on the safety and efficacy of vitamin E as a feed additive for all animal species (EFSA FEEDAP)Source →
    • Safety assessment of the substance alpha-tocopherol acetate for use in food contact materials (EFSA CEF)Source →
  • USFDAinactive ingredient database2 entries
    • Route: TOPICAL; Dosage form: OINTMENT; Potency: NASource →
    • Route: TOPICAL; Dosage form: AEROSOL, FOAM; Potency: NASource →
  • USEPAcommercial use observedEPA CPDat observed this chemical in 1 composition records across product categories including Personal care.
    • EPA CPDat observed this chemical in 1 composition records across product categories including Personal care.Source →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
    • openFDA substance registry classifies this ingredient as chemical.Source →
  • USFDAmarketed drug occurrenceFDA NDC lists this ingredient in 67 active drug products and 71 total products.
    • FDA NDC lists this ingredient in 67 active drug products and 71 total products.Source →

Expert safety opinions

Independent scientific assessments cited by the records we hold, with the year and link where the record gives one.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

  • JECFA

    Joint FAO/WHO Expert Committee on Food Additives

    No JECFA evaluation on file.

  • EFSA

    European Food Safety Authority

    • Assessment of a feed additive consisting of all-rac-alphatocopheryl acetate (vitamin E) for all animal species for the renewal of its authorisation (Jilin Beisha Pharmaceutical Co., Ltd) (EFSA FEEDAP)

      2021 · EU EFSA listing · Read the source →

    • Scientific Opinion on the safety and efficacy of vitamin E as a feed additive for all animal species (EFSA FEEDAP)

      2010 · EU EFSA listing · Read the source →

    • Safety assessment of the substance alpha-tocopherol acetate for use in food contact materials (EFSA CEF)

      2016 · EU EFSA listing · Read the source →

Evidence & sources

No graded research studies for .alpha.-tocopherol acetate, dl- yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

7 data sources

Where this comes from

  • EFSA OpenFoodTox

    regulatory · updated 2026-10-04

    Open →
  • EPA Chemical and Products Database

    exposure · updated January 7, 2008

    Open →
  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →
  • FDA Inactive Ingredient Database

    regulatory · updated 2026-01-09

    Open →
  • FDA National Drug Code Directory

    regulatory · updated 2027-12-31

    Open →
  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →
  • openFDA Substance

    registry · updated 2026-05-24

    Open →
Reference links (1)
Openfda substance

nikkajiweb.jst.go.jp

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Food use

Food-use source coverage is present in the current record.

Good fit

The ingredient appears in food-oriented source coverage or allowed-use references, which makes food use easier to support than a context with no domain signal at all.

Fragrance avoidance

No fragrance-linked caution surfaced in the current profile.

Good fit

This ingredient does not currently read as a fragrance-linked driver in the published evidence and hazard profile.

Where it has been recorded

How often FDA National Drug Code directory has listed .alpha.-tocopherol acetate, dl- in a product composition. These are source records, not Greenveil catalog products.

Source records

71

See products using .alpha.-tocopherol acetate, dl- →

Catalog

Found in these products

Their ingredient lists include .alpha.-tocopherol acetate, dl-; each product's own rating depends on its whole formula, so it is shown on the product page, not here.

Co-occurrence

Often appears with

Ingredients that frequently appear alongside .alpha.-tocopherol acetate, dl- in the catalog.